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Target
Transcriptional activator protein LuxR
Ligand
BDBM50356106
Substrate
n/a
Meas. Tech.
ChEMBL_775933 (CHEMBL1912676)
IC50
40000±n/a nM
Citation
 Boukraa, M; Sabbah, M; Soulère, L; El Efrit, ML; Queneau, Y; Doutheau, A AHL-dependent quorum sensing inhibition: synthesis and biological evaluation ofa-(N-alkyl-carboxamide)-¿-butyrolactones anda-(N-alkyl-sulfonamide)-¿-butyrolactones. Bioorg Med Chem Lett 21:6876-9 (2011) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXR_ALIFS | luxR
Type:
PROTEIN
Mol. Mass.:
28563.86
Organism:
Vibrio fischeri
Description:
ChEMBL_831639
Residue:
250
Sequence:
MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILDNYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLITGFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSNNDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILTGAIDCPYFKN
  
Inhibitor
Name:
BDBM50356106
Synonyms:
CHEMBL1911959
Type:
Small organic molecule
Emp. Form.:
C11H19NO2
Mol. Mass.:
197.2741
SMILES:
CCCCCNC(=O)C1CCCC1=O
Structure:
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