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Target
Stromelysin-1
Ligand
BDBM50290531
Substrate
n/a
Meas. Tech.
ChEBML_102100
IC50
900±n/a nM
Citation
 Esser, CK; Kevin, NJ; Yates, NA; Chapman, KT Solid-phase synthesis of a N-carboxyalkyl tripeptide combinatorial library Bioorg Med Chem Lett 7:2639-2644 (1997)    Article 
Target
Name:
Stromelysin-1
Synonyms:
MMP-3 | MMP3 | MMP3_HUMAN | Matrix metalloproteinase (2 and 3) | Matrix metalloproteinase 3 | Matrix metalloproteinase-3 | Matrix metalloproteinase-3 (MMP-3) | Matrix metalloproteinase-3 (MMP3) | SL-1 | STMY1 | Stromelysin 1 | Transin-1
Type:
Enzyme
Mol. Mass.:
53973.13
Organism:
Homo sapiens (Human)
Description:
P08254
Residue:
477
Sequence:
MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC
  
Inhibitor
Name:
BDBM50290531
Synonyms:
2-{(S)-1-[(S)-4-Guanidino-1-((S)-1-methoxycarbonyl-pentylcarbamoyl)-butylcarbamoyl]-3-phenyl-propylamino}-octanoic acid anion
Type:
Small organic molecule
Emp. Form.:
C31H51N6O6
Mol. Mass.:
603.7738
SMILES:
CCCCCCC(N[C@@H](CCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCC)C(=O)OC)C([O-])=O
Structure:
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