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Target
D(2) dopamine receptor
Ligand
BDBM50122733
Substrate
n/a
Meas. Tech.
ChEMBL_59633 (CHEMBL672423)
Ki
449±n/a nM
Citation
 Macchia, M; Cervetto, L; Demontis, GC; Longoni, B; Minutolo, F; Orlandini, E; Ortore, G; Papi, C; Sbrana, A; Macchia, B New N-n-propyl-substituted 3-aryl- and 3-cyclohexylpiperidines as partial agonists at the D4 dopamine receptor. J Med Chem 46:161-8 (2002) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50122733
Synonyms:
1-Propyl-3-o-tolyl-piperidine; hydrochloride | CHEMBL553258
Type:
Small organic molecule
Emp. Form.:
C15H23N
Mol. Mass.:
217.3498
SMILES:
CCCN1CCCC(C1)c1ccccc1C
Structure:
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