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Target
Transcriptional activator protein LuxR
Ligand
BDBM50373049
Substrate
n/a
Meas. Tech.
ChEMBL_466368 (CHEMBL932480)
IC50
13000±n/a nM
Citation
 Frezza, M; Soulère, L; Reverchon, S; Guiliani, N; Jerez, C; Queneau, Y; Doutheau, A Synthetic homoserine lactone-derived sulfonylureas as inhibitors of Vibrio fischeri quorum sensing regulator. Bioorg Med Chem 16:3550-6 (2008) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXR_ALIFS | luxR
Type:
PROTEIN
Mol. Mass.:
28563.86
Organism:
Vibrio fischeri
Description:
ChEMBL_831639
Residue:
250
Sequence:
MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILDNYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLITGFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSNNDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILTGAIDCPYFKN
  
Inhibitor
Name:
BDBM50373049
Synonyms:
CHEMBL408121
Type:
Small organic molecule
Emp. Form.:
C14H20N2O4S
Mol. Mass.:
312.385
SMILES:
O=C1OCCC1NS(=O)(=O)NCCCCc1ccccc1
Structure:
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