Reaction Details Report a problem with these data
Target
Sortase family protein
Ligand
BDBM50312644
Substrate
n/a
Meas. Tech.
ChEMBL_616480 (CHEMBL1101672)
IC50
127400±n/a nM
Citation
 Jeon, JE; Na, Z; Jung, M; Lee, HS; Sim, CJ; Nahm, K; Oh, KB; Shin, J Discorhabdins from the Korean marine sponge Sceptrella sp. J Nat Prod 73:258-62 (2010) [PubMed]  Article 
Target
Name:
Sortase family protein
Synonyms:
Sortase | Sortase A (SrtA)
Type:
Enzyme
Mol. Mass.:
23546.15
Organism:
Staphylococcus aureus
Description:
n/a
Residue:
206
Sequence:
MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQYDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVGVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK
  
Inhibitor
Name:
BDBM50312644
Synonyms:
CHEMBL1087525 | Didebromodiscorhabdin C
Type:
Small organic molecule
Emp. Form.:
C18H15N3O2
Mol. Mass.:
305.3306
SMILES:
O=C1C=C[C@]2(CCN=C3C2C2=NCCc4c[nH]c(c24)C3=O)C=C1 |r,c:2,7,25,t:11|
Structure:
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