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Target
Galectin-3
Ligand
BDBM50425519
Substrate
n/a
Meas. Tech.
ChEMBL_936059 (CHEMBL2319301)
Kd
22±n/a nM
Citation
 van Hattum, H; Branderhorst, HM; Moret, EE; Nilsson, UJ; Leffler, H; Pieters, RJ Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1. J Med Chem 56:1350-4 (2013) [PubMed]  Article 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM50425519
Synonyms:
CHEMBL2313626
Type:
Small organic molecule
Emp. Form.:
C28H32N6O10S
Mol. Mass.:
644.653
SMILES:
OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cccc(O)c2)[C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cccc(O)c1 |r|
Structure:
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