Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM50428120
Substrate
n/a
Meas. Tech.
ChEMBL_944966 (CHEMBL2344457)
IC50
46±n/a nM
Citation
 Brabez, N; Saunders, K; Nguyen, KL; Jayasundera, TB; Weber, C; Lynch, RM; Chassaing, G; Lavielle, S; Hruby, VJ Multivalent Interactions: Synthesis and Evaluation of Melanotropin Multimers - Tools for Melanoma Targeting. ACS Med Chem Lett 4:98-102 (2013) [PubMed]  Article 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM50428120
Synonyms:
CHEMBL2331673
Type:
Small organic molecule
Emp. Form.:
C275H356N100O46
Mol. Mass.:
5798.4115
SMILES:
n/a
Structure:
Search PDB for entries with ligand similarity: