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Target
Cannabinoid receptor 2
Ligand
BDBM50041442
Substrate
n/a
Meas. Tech.
ChEMBL_1446274 (CHEMBL3373668)
EC50
40±n/a nM
Citation
 Iwata, Y; Ando, K; Taniguchi, K; Koba, N; Sugiura, A; Sudo, M Identification of a highly potent and selective CB2 agonist, RQ-00202730, for the treatment of irritable bowel syndrome. Bioorg Med Chem Lett 25:236-40 (2014) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50041442
Synonyms:
CHEMBL3357388
Type:
Small organic molecule
Emp. Form.:
C24H35N5O4S
Mol. Mass.:
489.631
SMILES:
CC(=O)N1CCC(Cn2c(CC(C)(C)C)nc3cc(ccc23)S(=O)(=O)C2CN(C2)C(N)=O)CC1
Structure:
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