Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50069695
Substrate
n/a
Meas. Tech.
ChEMBL_1466939 (CHEMBL3406417)
Kd
44000±n/a nM
Citation
 Mishra, RC; Gundala, SR; Karna, P; Lopus, M; Gupta, KK; Nagaraju, M; Hamelberg, D; Tandon, V; Panda, D; Reid, MD; Aneja, R Design, synthesis and biological evaluation of di-substituted noscapine analogs as potent and microtubule-targeted anticancer agents. Bioorg Med Chem Lett 25:2133-40 (2015) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50069695
Synonyms:
CHEMBL3400852
Type:
Small organic molecule
Emp. Form.:
C23H22BrNO8
Mol. Mass.:
520.327
SMILES:
[H][C@@]1(OC(=O)c2c1ccc(OC)c2OC(C)=O)[C@]1([H])N(C)CCc2c(Br)c3OCOc3c(OC)c12 |r|
Structure:
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