Reaction Details Report a problem with these data
Target
Stromal cell-derived factor 1
Ligand
BDBM50180878
Substrate
n/a
Meas. Tech.
ChEMBL_1585148 (CHEMBL3820796)
Kd
1100000±n/a nM
Citation
 Smith, EW; Nevins, AM; Qiao, Z; Liu, Y; Getschman, AE; Vankayala, SL; Kemp, MT; Peterson, FC; Li, R; Volkman, BF; Chen, Y Structure-Based Identification of Novel Ligands Targeting Multiple Sites within a Chemokine-G-Protein-Coupled-Receptor Interface. J Med Chem 59:4342-51 (2016) [PubMed]  Article 
Target
Name:
Stromal cell-derived factor 1
Synonyms:
CXCL12 | Chemokine CXCL12 | SDF1 | SDF1A | SDF1B | SDF1_HUMAN
Type:
Enzyme
Mol. Mass.:
10677.83
Organism:
Homo sapiens (Human)
Description:
P48061
Residue:
93
Sequence:
MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM
  
Inhibitor
Name:
BDBM50180878
Synonyms:
CHEMBL3818321
Type:
Small organic molecule
Emp. Form.:
C19H27FNO5P
Mol. Mass.:
399.3935
SMILES:
CC(C)O.CCCOc1ccc(cc1)C(Nc1ccc(F)cc1)P(O)(O)=O
Structure:
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