Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94976
Substrate
n/a
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94976
Synonyms:
5-bromo-2-furancarboxylic acid [2-oxo-2-[(4,5,6-trifluoro-1,3-benzothiazol-2-yl)amino]ethyl] ester | 5-bromofuran-2-carboxylic acid [2-keto-2-[(4,5,6-trifluoro-1,3-benzothiazol-2-yl)amino]ethyl] ester | MLS001005119 | SMR000377977 | [2-oxidanylidene-2-[[4,5,6-tris(fluoranyl)-1,3-benzothiazol-2-yl]amino]ethyl] 5-bromanylfuran-2-carboxylate | [2-oxo-2-[(4,5,6-trifluoro-1,3-benzothiazol-2-yl)amino]ethyl] 5-bromofuran-2-carboxylate | cid_2340585
Type:
Small organic molecule
Emp. Form.:
C14H6BrF3N2O4S
Mol. Mass.:
435.173
SMILES:
Fc1cc2sc(NC(=O)COC(=O)c3ccc(Br)o3)nc2c(F)c1F
Structure:
Search PDB for entries with ligand similarity: