Reaction Details Report a problem with these data
Target
Amine oxidase [flavin-containing] B
Ligand
BDBM115181
Substrate
n/a
Meas. Tech.
MAO Enzyme Assays
pH
7.4±n/a
IC50
14.6± 17 nM
Comments
extracted
Citation
 Geldenhuys, WJ; Kochi, A; Lin, L; Sutariya, V; Dluzen, DE; Van der Schyf, CJ; Lim, MH Methyl Yellow: A Potential Drug Scaffold for Parkinson's Disease. Chembiochem 15:1591-8 (2014) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM115181
Synonyms:
(E)-N,N-dimethyl-4-(phenyldiazenyl)aniline | Methyl yellow (MY)
Type:
Small organic molecule
Emp. Form.:
C14H15N3
Mol. Mass.:
225.289
SMILES:
CN(C)c1ccc(cc1)\N=N\c1ccccc1
Structure:
Search PDB for entries with ligand similarity: