Reaction Details
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Target
Dihydrofolate reductase
Ligand
BDBM18069
Substrate
n/a
Meas. Tech.
DHFR Inhibition Assay
IC50
4.3e+4± 2e+3 nM
Citation
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More Info.:
Target
Name:
Dihydrofolate reductase
Synonyms:
Dihydrofolate reductase (DfrK)
Type:
Protein
Mol. Mass.:
19251.04
Organism:
Staphylococcus aureus
Description:
C7C2U7
Residue:
163
Sequence:
MKVSLIAAMDKNRVIGKENDIPWRIPEDWEYVKNTTKGYPIILGRKNLESIGRALPGRRNIILTRDKGFSFNGCEIVHSIEDVFELCNSEEEIFIFGGEQIYNLFLPYVEKMYITKIHYEFEGDTFFPEVNYEEWNEVSVTQGITNEKNPYTYYFHIYERKAS