Reaction Details Report a problem with these data
Target
Somatostatin receptor type 2
Ligand
BDBM405612
Substrate
n/a
Meas. Tech.
cAMP Assay
EC50
<10±n/a nM
Citation
 Zhao, J; Wang, S; Zhu, Y Somatostatin modulators and uses thereof US Patent  US10597377 Publication Date 3/24/2020 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM405612
Synonyms:
US10351547, Compound 2-26 | US10597377, Compound 2-26
Type:
Small organic molecule
Emp. Form.:
C29H28F2N4O
Mol. Mass.:
486.5556
SMILES:
CCNCC1CN(C1)c1c(cnc2ccc(cc12)-c1cc(F)cc(c1)C(N)=O)-c1cc(C)cc(F)c1
Structure:
Search PDB for entries with ligand similarity: