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Target
Stearoyl-CoA desaturase
Ligand
BDBM482910
Substrate
n/a
Meas. Tech.
Compound Profiling Methods
IC50
20.0±n/a nM
Citation
 Wrona, I; Tivitmahaisoon, P; Tardiff, D; Pandya, B; Ozboya, K; Lucas, M; Bourdonnec, BL Compounds and uses thereof US Patent  US10919885 Publication Date 2/16/2021 
Target
Name:
Stearoyl-CoA desaturase
Synonyms:
Acyl-CoA desaturase | FADS5 | SCD | SCD1 | SCDOS | SCD_HUMAN | Stearoyl-CoA (SCD1) | Stearoyl-CoA desaturase 1
Type:
Enzyme
Mol. Mass.:
41537.27
Organism:
Homo sapiens (Human)
Description:
O00767
Residue:
359
Sequence:
MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDDIRPDIKDDIYDPTYKDKEGPSPKVEYVWRNIILMSLLHLGALYGITLIPTCKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLMMCFILPTLVPWYFWGETFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNYHHSFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG
  
Inhibitor
Name:
BDBM482910
Synonyms:
US10919885, Compound No. 58
Type:
Small organic molecule
Emp. Form.:
C17H15FN4O2
Mol. Mass.:
326.325
SMILES:
CC(=C)c1cc(no1)C(=O)Nc1cnn(Cc2cccc(F)c2)c1
Structure:
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