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Target
Stimulator of interferon genes protein [149-345,G230A,H232R,R293Q]
Ligand
BDBM598391
Substrate
n/a
Meas. Tech.
Surface Plasmon Resonance (SPR)
Kd
52000±n/a nM
Citation
 Morrow, BJ; Camerino, MA; Walker, SR; Stevenson, GI; Stupple, PA Substituted condensed thiophenes as modulators of sting US Patent  US11613525 Publication Date 3/28/2023 
Target
Name:
Stimulator of interferon genes protein [149-345,G230A,H232R,R293Q]
Synonyms:
ERIS | MITA | STING | STING1 | STING_HUMAN | TMEM173
Type:
Protein
Mol. Mass.:
22434.40
Organism:
Human
Description:
Q86WV6[149-345,G230A,H232R,R293Q]
Residue:
197
Sequence:
EKGNFNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDRAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCQTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVGS
  
Inhibitor
Name:
BDBM598391
Synonyms:
US11613525, Example 113
Type:
Small organic molecule
Emp. Form.:
C19H16ClNO5S
Mol. Mass.:
405.852
SMILES:
COCc1cc(OCc2c(sc3cccc(Cl)c23)C(O)=O)ccc1C(N)=O
Structure:
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