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Target
Sentrin-specific protease 8
Ligand
BDBM73835
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
2460±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM73835
Synonyms:
1-({4-[(4-fluorobenzyl)oxy]phenyl}carbonothioyl)pyrrolidine | MLS001163368 | SMR000497283 | [4-(4-fluorobenzyl)oxyphenyl]-pyrrolidino-methanethione | [4-[(4-fluorophenyl)methoxy]phenyl]-(1-pyrrolidinyl)methanethione | [4-[(4-fluorophenyl)methoxy]phenyl]-pyrrolidin-1-yl-methanethione | [4-[(4-fluorophenyl)methoxy]phenyl]-pyrrolidin-1-ylmethanethione | cid_800285
Type:
Small organic molecule
Emp. Form.:
C18H18FNOS
Mol. Mass.:
315.405
SMILES:
Fc1ccc(COc2ccc(cc2)C(=S)N2CCCC2)cc1
Structure:
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