Reaction Details Report a problem with these data
Target
X-box-binding protein 1
Ligand
BDBM54242
Substrate
n/a
Meas. Tech.
XBP1 DR counterscreen for CHOP
IC50
4750±n/a nM
Citation
 PubChem, PC XBP1 DR counterscreen for CHOP PubChem Bioassay (2011)[AID] 
Target
Name:
X-box-binding protein 1
Synonyms:
TREB5 | XBP1 | XBP1_HUMAN | XBP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28704.14
Organism:
Homo sapiens (Human)
Description:
gi_47678753
Residue:
261
Sequence:
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVPYQPPFLCQWGRHQPSWKPLMN
  
Inhibitor
Name:
BDBM54242
Synonyms:
1-[5-(2-Ethylsulfanyl-ethyl)-[1,3,4]thiadiazol-2-yl]-3-(3-trifluoromethyl-phenyl)-urea | 1-[5-(2-ethylsulfanylethyl)-1,3,4-thiadiazol-2-yl]-3-[3-(trifluoromethyl)phenyl]urea | 1-[5-[2-(ethylthio)ethyl]-1,3,4-thiadiazol-2-yl]-3-[3-(trifluoromethyl)phenyl]urea | MLS000587564 | SMR000211593 | cid_3840152
Type:
Small organic molecule
Emp. Form.:
C14H15F3N4OS2
Mol. Mass.:
376.42
SMILES:
CCSCCc1nnc(NC(=O)Nc2cccc(c2)C(F)(F)F)s1
Structure:
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