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Target
DNA dC->dU-editing enzyme APOBEC-3A
Ligand
BDBM48480
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay
Temperature
298.15±n/a K
IC50
5610±n/a nM
Comments
extracted
Citation
 PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3A
Synonyms:
ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23013.77
Organism:
Homo sapiens (Human)
Description:
gi_21955158
Residue:
199
Sequence:
MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
  
Inhibitor
Name:
BDBM48480
Synonyms:
5-cyclopentylidene-2-sulfanylidene-1,3-thiazolidin-4-one | 5-cyclopentylidene-2-sulfanylidene-4-thiazolidinone | 5-cyclopentylidene-2-thioxo-1,3-thiazolidin-4-one | 5-cyclopentylidene-2-thioxo-thiazolidin-4-one | MLS000532537 | SMR000137476 | cid_2844976
Type:
Small organic molecule
Emp. Form.:
C8H9NOS2
Mol. Mass.:
199.293
SMILES:
[#16]-[#6]-1=[#7]-[#6](=O)\[#6](-[#16]-1)=[#6]-1/[#6]-[#6]-[#6]-[#6]-1 |t:1|
Structure:
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