Reaction Details Report a problem with these data
Target
Lymphocyte antigen 96
Ligand
BDBM50501805
Substrate
n/a
Meas. Tech.
ChEMBL_1805484 (CHEMBL4304843)
IC50
4570±n/a nM
Citation
 Liu, Z; Chen, L; Yu, P; Zhang, Y; Fang, B; Wu, C; Luo, W; Chen, X; Li, C; Liang, G Discovery of 3-(Indol-5-yl)-indazole Derivatives as Novel Myeloid Differentiation Protein 2/Toll-like Receptor 4 Antagonists for Treatment of Acute Lung Injury. J Med Chem 62:5453-5469 (2019) [PubMed]  Article 
Target
Name:
Lymphocyte antigen 96
Synonyms:
ESOP-1 | Esop1 | LY96_MOUSE | Ly-96 | Ly96 | Lymphocyte antigen 96 | Md2 | Protein MD-2
Type:
PROTEIN
Mol. Mass.:
18394.96
Organism:
Mus musculus
Description:
ChEMBL_118313
Residue:
160
Sequence:
MLPFILFSTLLSPILTESEKQQWFCNSSDAIISYSYCDHLKFPISISSEPCIRLRGTNGFVHVEFIPRGNLKYLYFNLFISVNSIELPKRKEVLCHGHDDDYSFCRALKGETVNTSIPFSFEGILFPKGHYRCVAEAIAGDTEEKLFCLNFTIIHRRDVN
  
Inhibitor
Name:
BDBM50501805
Synonyms:
CHEMBL4468247
Type:
Small organic molecule
Emp. Form.:
C20H19ClN4O2
Mol. Mass.:
382.843
SMILES:
OCCn1ccc2cc(ccc12)-c1n[nH]c2ccc(NC(=O)CCCl)cc12
Structure:
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