Reaction Details Report a problem with these data
Target
Integrase
Ligand
BDBM50154405
Substrate
n/a
Meas. Tech.
ChEMBL_912206 (CHEMBL3055360)
IC50
15381546±n/a nM
Citation
  TBA Med Chem Res 21:165-173 (2012)    Article 
Target
Name:
Integrase
Synonyms:
pol
Type:
PROTEIN
Mol. Mass.:
32203.43
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_106649
Residue:
288
Sequence:
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50154405
Synonyms:
4-(5-Ethyl-5H-[1,3]dioxolo[4,5-f]indol-6-yl)-2,4-dioxo-butyric acid methyl ester | CHEMBL187971
Type:
Small organic molecule
Emp. Form.:
C16H15NO6
Mol. Mass.:
317.2934
SMILES:
CCn1c(cc2cc3OCOc3cc12)C(=O)CC(=O)C(=O)OC
Structure:
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