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Target
CDGSH iron-sulfur domain-containing protein 2
Ligand
BDBM50350486
Substrate
n/a
Meas. Tech.
ChEMBL_1869768 (CHEMBL4370834)
IC50
29770±n/a nM
Citation
 Geldenhuys, WJ; Skolik, R; Konkle, ME; Menze, MA; Long, TE; Robart, AR Binding of thiazolidinediones to the endoplasmic reticulum protein nutrient-deprivation autophagy factor-1. Bioorg Med Chem Lett 29:901-904 (2019) [PubMed]  Article 
Target
Name:
CDGSH iron-sulfur domain-containing protein 2
Synonyms:
CDGSH iron-sulfur domain-containing protein 2 | CDGSH2 | CISD2 | CISD2_HUMAN | ERIS | Endoplasmic reticulum intermembrane small protein | Miner1 | MitoNEET-related 1 protein | NAF-1 | Nutrient-deprivation autophagy factor-1 | ZCD2
Type:
PROTEIN
Mol. Mass.:
15289.10
Organism:
Homo sapiens
Description:
ChEMBL_119149
Residue:
135
Sequence:
MVLESVARIVKVQLPAYLKRLPVPESITGFARLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTGDNVGPLILKKKEV
  
Inhibitor
Name:
BDBM50350486
Synonyms:
CHEMBL602048
Type:
Small organic molecule
Emp. Form.:
C18H25NO3S
Mol. Mass.:
335.461
SMILES:
CC(C)(C)c1cc(Cc2sc(=O)[nH]c2O)cc(c1O)C(C)(C)C
Structure:
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