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Target
Fatty acid-binding protein 5
Ligand
BDBM50574783
Substrate
n/a
Meas. Tech.
ChEMBL_2123366 (CHEMBL4832599)
Kd
14090±n/a nM
Citation
 He, YL; Chen, MT; Wang, T; Zhang, MM; Li, YX; Wang, HY; Ding, N Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus. Eur J Med Chem 224:0 (2021) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein 5
Synonyms:
FABP5 | FABP5_HUMAN | Fatty acid binding protein epidermal | Fatty acid-binding protein 5 (FABP5)
Type:
Enzyme
Mol. Mass.:
15164.79
Organism:
Homo sapiens (Human)
Description:
Q01469
Residue:
135
Sequence:
MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVECVMNNVTCTRIYEKVE
  
Inhibitor
Name:
BDBM50574783
Synonyms:
CHEMBL4864312
Type:
Small organic molecule
Emp. Form.:
C26H21F2NO5S
Mol. Mass.:
497.51
SMILES:
COc1c(cc(c2ccccc12)S(=O)(=O)Nc1ccc(F)c(CC(O)=O)c1)-c1ccc(F)cc1C
Structure:
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