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Target
P2Y purinoceptor 6
Ligand
BDBM50405423
Substrate
n/a
Meas. Tech.
ChEMBL_2265218
IC50
31600±n/a nM
Citation
 Jung, YH; Shah, Q; Lewicki, SA; Pramanik, A; Gopinatth, V; Pelletier, J; Sévigny, J; Iqbal, J; Jacobson, KA Synthesis and pharmacological characterization of multiply substituted 2H-chromene derivatives as P2Y Bioorg Med Chem Lett 75:0 (2022) [PubMed] 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2Y purinoceptor 6 | P2Y6 | P2ry6
Type:
PROTEIN
Mol. Mass.:
36747.19
Organism:
Mus musculus
Description:
ChEMBL_120945
Residue:
328
Sequence:
MEQDNGTIQAPGLPPTTCVYREDFKRLLLTPVYSVVLVVGLPLNICVIAQICASRRTLTRSAVYTLNLALADLMYACSLPLLIYNYARGDHWPFGDLACRFVRFLFYANLHGSILFLTCISFQRYLGICHPLASWHKRGGRRAAWVVCGVVWLAVTAQCLPTAVFAATGIQRNRTVCYDLSPPILSTRYLPYGMALTVIGFLLPFIALLACYCRMARRLCRQDGPAGPVAQERRSKAARMAVVVAAVFAISFLPFHITKTAYLAVRSTPGVSCPVLETFAAAYKGTRPFASVNSVLDPILFYFTQQKFRRQPHDLLQRLTAKWQRQRV
  
Inhibitor
Name:
BDBM50405423
Synonyms:
CHEMBL5283362
Type:
Small organic molecule
Emp. Form.:
C19H12F3NO4
Mol. Mass.:
375.2981
SMILES:
OCc1ccc(cc1)C#Cc1ccc2OC(C(=Cc2c1)[N+]([O-])=O)C(F)(F)F |c:17|
Structure:
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