Reaction Details Report a problem with these data
Target
Arginase-1
Ligand
BDBM50608139
Substrate
n/a
Meas. Tech.
ChEMBL_2272756
Ki
90000±n/a nM
Citation
 Xiao, YC; Yu, JL; Dai, QQ; Li, G; Li, GB Targeting Metalloenzymes by Boron-Containing Metal-Binding Pharmacophores. J Med Chem 64:17706-17727 (2021) [PubMed] 
Target
Name:
Arginase-1
Synonyms:
ARG1 | ARGI1_BOVIN | Liver-type arginase | Type I arginase
Type:
PROTEIN
Mol. Mass.:
35008.90
Organism:
Bos taurus
Description:
ChEMBL_474406
Residue:
322
Sequence:
MSSKPQSIGVIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKELECDVKDYGDLSFADNLDDSPFQIVKNPRCVGKASEKLADVVAEVKKTGRISLVLGGDHSLAIGSISGHARVHPDLCVIWVDAHTDINTPLTTKTGNLHGQPVSFLLKELKEKMPEVPGFYWVAPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVQGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTTVAITMACFGVAREGNHKPIDYLSPPK
  
Inhibitor
Name:
BDBM50608139
Synonyms:
CHEMBL5287570
Type:
Small organic molecule
Emp. Form.:
C6H14N2O4S
Mol. Mass.:
210.251
SMILES:
N[C@@H](CCCCS(N)(=O)=O)C(O)=O |r|
Structure:
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