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Target
Formyl peptide receptor-related sequence 1
Ligand
BDBM50186957
Substrate
n/a
Meas. Tech.
ChEMBL_2275453
EC50
>1000±n/a nM
Citation
 Maciuszek, M; Cacace, A; Brennan, E; Godson, C; Chapman, TM Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential. Eur J Med Chem 213:0 (2021) [PubMed] 
Target
Name:
Formyl peptide receptor-related sequence 1
Synonyms:
FMLP-R-I | FMLP-related receptor I | FPRS1_MOUSE | Formyl peptide receptor related sequence 1 | Formyl peptide receptor-like 1 | Fpr-s1 | Fpr2 | Fpr3 | Fprl1 | LXA4 receptor | Lipoxin A4 receptor | Lxa4r | N-formyl peptide receptor 2 | N-formyl peptide receptor 3
Type:
PROTEIN
Mol. Mass.:
39532.25
Organism:
Mus musculus
Description:
ChEMBL_109574
Residue:
351
Sequence:
METNYSIPLNGSDVVIYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIAVDVNLFGSVFLIAVIALDRCICVLHPVWAQNHRTVSLARNVVVGSWIFALILTLPLFLFLTTVRDARGDVHCRLSFVSWGNSVEERLNTAITFVTTRGIIRFIVSFSLPMSFVAICYGLITTKIHKKAFVNSSRPFRVLTGVVASFFICWFPFQLVALLGTVWLKEMQFSGSYKIIGRLVNPTSSLAFFNSCLNPILYVFMGQDFQERLIHSLSSRLQRALSEDSGHISDTRTNLASLPEDIEIKAI
  
Inhibitor
Name:
BDBM50186957
Synonyms:
1-(3-tert-butyl-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-chlorophenyl)urea | CHEMBL377226
Type:
Small organic molecule
Emp. Form.:
C21H23ClN4O2
Mol. Mass.:
398.886
SMILES:
Cn1c(c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n1-c1ccccc1)C(C)(C)C
Structure:
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