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Target
Bcl-2-related protein A1
Ligand
BDBM50610578
Substrate
n/a
Meas. Tech.
ChEMBL_2281551
IC50
264±n/a nM
Citation
 Li, X; Dou, J; You, Q; Jiang, Z Inhibitors of BCL2A1/Bfl-1 protein: Potential stock in cancer therapy. Eur J Med Chem 220:0 (2021) [PubMed] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:
Apoptosis regulator protein
Mol. Mass.:
20130.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
  
Inhibitor
Name:
BDBM50610578
Synonyms:
CHEMBL5283854
Type:
Small organic molecule
Emp. Form.:
C17H16ClN3O3S
Mol. Mass.:
377.845
SMILES:
Cl.Cc1cs\c(=N/c2ccccc2)n1\N=C\c1ccc(O)c(O)c1O
Structure:
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