Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50370759
Substrate
n/a
Meas. Tech.
ChEMBL_2303216
Ki
71±n/a nM
Citation
 Turnaturi, R; Montenegro, L; Marrazzo, A; Parenti, R; Pasquinucci, L; Parenti, C Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review. Eur J Med Chem 155:492-502 (2018) [PubMed] 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50370759
Synonyms:
CHEMBL4176080
Type:
Small organic molecule
Emp. Form.:
C24H29N3O2
Mol. Mass.:
391.506
SMILES:
[H][C@@]12C[C@@]([H])(N(CC1)C(=O)OCc1ccccc1)c1cc(ccc21)N1CCN(C)CC1 |r|
Structure:
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