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Target
Enoyl-[acyl-carrier-protein] reductase [NADH]
Ligand
BDBM50242321
Substrate
n/a
Meas. Tech.
ChEMBL_509155 (CHEMBL1008999)
IC50
75000±n/a nM
Citation
 Cao, S; Lee, AS; Huang, Y; Flotow, H; Ng, S; Butler, MS; Buss, AD Agonodepsides a and B: two new depsides from a filamentous fungus F7524. J Nat Prod 65:1037-8 (2002) [PubMed]  Article 
Target
Name:
Enoyl-[acyl-carrier-protein] reductase [NADH]
Synonyms:
Enoyl-ACP Reductase (InhA) | Enoyl-[acyl-carrier-protein] reductase | Enoyl-[acyl-carrier-protein] reductase [NADH] | INHA_MYCTU | NADH-dependent enoyl-ACP reductase | inhA
Type:
Enzyme
Mol. Mass.:
28526.00
Organism:
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Description:
P9WGR1
Residue:
269
Sequence:
MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL
  
Inhibitor
Name:
BDBM50242321
Synonyms:
Agonodepside A | CHEMBL454588
Type:
Small organic molecule
Emp. Form.:
C23H26O5
Mol. Mass.:
382.4495
SMILES:
C\C=C(/C)c1cc(O)c(C)c(OC(=O)c2c(O)c(C)c(O)cc2\C(C)=C\C)c1
Structure:
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