Reaction Details Report a problem with these data
Target
Phospholipase A2, membrane associated
Ligand
BDBM50263051
Substrate
n/a
Meas. Tech.
ChEMBL_489271 (CHEMBL990827)
IC50
>1600±n/a nM
Citation
 Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem 51:4708-14 (2008) [PubMed]  Article 
Target
Name:
Phospholipase A2, membrane associated
Synonyms:
PA2GA_MOUSE | Pla2g2a
Type:
PROTEIN
Mol. Mass.:
16162.44
Organism:
Mus musculus
Description:
ChEMBL_352635
Residue:
146
Sequence:
MKVLLLLAASIMAFGSIQVQGNIAQFGEMIRLKTGKRAELSYAFYGCHCGLGGKGSPKDATDRCCVTHDCCYKSLEKSGCGTKLLKYKYSHQGGQITCSANQNSCQKRLCQCDKAAAECFARNKKTYSLKYQFYPNMFCKGKKPKC
  
Inhibitor
Name:
BDBM50263051
Synonyms:
2-(1-(2-amino-2-oxoacetyl)-2-(isobutyl)-3-(ophenylbenzyl)indolizin-8-yloxy)acetic acid | CHEMBL478820
Type:
Small organic molecule
Emp. Form.:
C29H28N2O5
Mol. Mass.:
484.543
SMILES:
CC(C)Cc1c(Cc2ccccc2-c2ccccc2)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O
Structure:
Search PDB for entries with ligand similarity: