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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50285915
Substrate
n/a
Meas. Tech.
ChEMBL_79817 (CHEMBL695236)
IC50
6.1±n/a nM
Citation
 Kempf, DJ; Flentge, CA; Wideburg, NE; Saldivar, A; Vasavanonda, S; Norbeck, DW Evaluation of substituted benzamides as P2 ligands for symmetry-based inhibitors of HIV protease Bioorg Med Chem Lett 5:2725-2728 (1995)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50285915
Synonyms:
CHEMBL91657 | [(1S,2S,4S)-4-(4-Amino-2-chloro-benzoylamino)-1-benzyl-2-hydroxy-5-phenyl-pentyl]-carbamic acid benzyl ester
Type:
Small organic molecule
Emp. Form.:
C33H34ClN3O4
Mol. Mass.:
572.094
SMILES:
Nc1ccc(C(=O)N[C@H](C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)Cc2ccccc2)c(Cl)c1
Structure:
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