Target
Melatonin receptor type 1A
Ligand
BDBM50086019
Substrate
n/a
Meas. Tech.
ChEMBL_105101 (CHEMBL715945)
Ki
195±n/a nM
Citation
 Faust, RGarratt, PJJones, RYeh, LKTsotinis, APanoussopoulou, MCalogeropoulou, TTeh, MTSugden, D Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1-a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles. J Med Chem 43:1050-61 (2000) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50086019
Synonyms:
CHEMBL9765 | N-[2-(6H-Isoindolo[2,1-a]indol-11-yl)-ethyl]-acetamide
Type:
Small organic molecule
Emp. Form.:
C19H18N2O
Mol. Mass.:
290.359
SMILES:
CC(=O)NCCc1c2-c3ccccc3Cn2c2ccccc12
Structure:
Search PDB for entries with ligand similarity: