Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50130282
Substrate
n/a
Meas. Tech.
ChEMBL_3778 (CHEMBL619854)
Ki
32.0±n/a nM
Citation
 Glennon, RA Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). J Med Chem 46:2795-812 (2003) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50130282
Synonyms:
CHEMBL13049 | Naphthalene-1-sulfonic acid methyl-[1-methyl-3-(3-methyl-piperidin-1-yl)-propyl]-amide | R,R-Naphthalene-1-sulfonic acid methyl-[1-methyl-3-(3-methyl-piperidin-1-yl)-propyl]-amide | R-Naphthalene-1-sulfonic acid methyl-[1-methyl-3-(3-methyl-piperidin-1-yl)-propyl]-amide
Type:
Small organic molecule
Emp. Form.:
C21H30N2O2S
Mol. Mass.:
374.54
SMILES:
CC(CCN1CCCC(C)C1)N(C)S(=O)(=O)c1cccc2ccccc12
Structure:
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