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Target
Stearoyl-CoA desaturase
Ligand
BDBM50371037
Substrate
n/a
Meas. Tech.
ChEMBL_438636 (CHEMBL888967)
IC50
30±n/a nM
Citation
 Zhao, H; Serby, MD; Smith, HT; Cao, N; Suhar, TS; Surowy, TK; Camp, HS; Collins, CA; Sham, HL; Liu, G Discovery of 1-(4-phenoxypiperidin-1-yl)-2-arylaminoethanone stearoyl-CoA desaturase 1 inhibitors. Bioorg Med Chem Lett 17:3388-91 (2007) [PubMed]  Article 
Target
Name:
Stearoyl-CoA desaturase
Synonyms:
Acyl-CoA desaturase | FADS5 | SCD | SCD1 | SCDOS | SCD_HUMAN | Stearoyl-CoA (SCD1) | Stearoyl-CoA desaturase 1
Type:
Enzyme
Mol. Mass.:
41537.27
Organism:
Homo sapiens (Human)
Description:
O00767
Residue:
359
Sequence:
MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDDIRPDIKDDIYDPTYKDKEGPSPKVEYVWRNIILMSLLHLGALYGITLIPTCKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLMMCFILPTLVPWYFWGETFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNYHHSFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG
  
Inhibitor
Name:
BDBM50371037
Synonyms:
CHEMBL230609
Type:
Small organic molecule
Emp. Form.:
C17H18Cl2N4O2
Mol. Mass.:
381.256
SMILES:
Clc1ccccc1OC1CCN(CC1)C(=O)CNc1nccnc1Cl
Structure:
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