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Target
Sentrin-specific protease 2
Ligand
BDBM50164846
Substrate
n/a
Meas. Tech.
ChEMBL_1576308 (CHEMBL3801658)
IC50
2800±n/a nM
Citation
 Xie, W; Wang, Z; Zhang, J; Wang, L; Zhao, Y; Zhou, H Development and evaluation of a highly reliable assay for SUMO-specific protease inhibitors. Bioorg Med Chem Lett 26:2124-8 (2016) [PubMed]  Article 
Target
Name:
Sentrin-specific protease 2
Synonyms:
KIAA1331 | SENP2 | SENP2_HUMAN | Sentrin-specific protease 2 (SENP2)
Type:
Protein
Mol. Mass.:
67890.62
Organism:
Homo sapiens (Human)
Description:
Q9HC62
Residue:
589
Sequence:
MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL
  
Inhibitor
Name:
BDBM50164846
Synonyms:
CHEMBL3799152
Type:
Small organic molecule
Emp. Form.:
C29H24N2O2
Mol. Mass.:
432.5131
SMILES:
O=C(Nc1cccc(CNC(=O)c2cccc(c2)-c2ccccc2)c1)\C=C\c1ccccc1
Structure:
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