Reaction Details Report a problem with these data
Target
Urease
Ligand
BDBM50067892
Substrate
n/a
Meas. Tech.
Urease Inhibition Assay
pH
7±n/a
Temperature
310.15±n/a K
Ki
2.20e+5± 4.0e+4 nM
Comments
extracted
Citation
 Kumar, S; Kayastha, AM Inhibition studies of soybean (Glycine max) urease with heavy metals, sodium salts of mineral acids, boric acid, and boronic acids. J Enzyme Inhib Med Chem 25:646-52 (2010) [PubMed]  Article 
Target
Name:
Urease
Synonyms:
n/a
Type:
Enzyme
Mol. Mass.:
90703.11
Organism:
Glycine max (Soybean)
Description:
Q949H4
Residue:
837
Sequence:
MKLSPREIEKLDLHNAGYLAQKRLARGLRLNYVETVALIATQILEFVRDGEKTVAQLMCIGRELLGRKQVLPAVPHLVESVQVEATFRDGTKLVTIHDLFACENGNLELALFGSFLPVPSLDKFTENEEDHRTPGEIICRSENLILNPRRNAIILRVVNKGDRPIQVGSHYHFIEVNPYLTFDRRKAYGMRLNIAAGNATRFEPGECKSVVLVSIGGNKVIRGGNNIADGPVNDSNCRAAMKAVVTRGFGHVEEENAREGVTGEDYSLTTVISREEYAHKYGPTTGDKIRLGDTDLFAEIEKDFAVYGDECVFGGGKVIRDGMGQSSGHPPEGSLDTVITNAVIIDYTGIIKADIGIKDGLIISTGKAGNPDIMNDVFPNMIIGANTEVIAGEGLIVTAGAIDCHVHFICPQLVYDAVTSGITTLVGGGTGPADGTRATTCTPAPNQMKLMLQSTDDMPLNFGFTGKGNSAKPDELHEIIRAGAMGLKLHEDWGTTPAAIDSCLTVADQYDIQVNIHTDTLNESGFVEHTIAAFKGRTIHTYHSEGAGGGHAPDIIKVCGEKNVLPSSTNPTRPYTHNTIDEHLDMLMVCHHLNKNIPEDVAFAESRIRAETIAAEDILHDKGAISIISSDSQAMGRIGEVISRTWQTADKMKSQRGPLQPGEDNDNFRIKRYVAKYTINPAIANGLSQYVGSVEAGKLADLVLWKPSFFGAKPEMVIKGGEVAYANMGDPNASIPTPEPVIMRPMFGAFGKAGSSHSIAFVSKAALDEGVKASYGLNKRVEAVKNVRKLTKRDMKLNDTLPQITVDPETYTVTADGEVLTCTAAKTVPLSRNYFLF
  
Inhibitor
Name:
BDBM50067892
Synonyms:
4-Bromophenyl-boronic acid | 4-bromo phenyl boronic acid | 4-bromophenyl boronic acid | 4-bromophenylboronic acid | Boronic acid derivative | CHEMBL20866
Type:
Small organic molecule
Emp. Form.:
C6H6BBrO2
Mol. Mass.:
200.826
SMILES:
OB(O)c1ccc(Br)cc1
Structure:
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