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Target
Cannabinoid receptor 2
Ligand
BDBM435493
Substrate
n/a
Meas. Tech.
In Vitro Assay
EC50
15.0±n/a nM
Citation
 Riether, D; Binder, FP; Doods, H; Mueller, SG; Nicholson, JR; Sauer, A (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles US Patent  US11084810 Publication Date 8/10/2021 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM435493
Synonyms:
US10570125, Example 7 | US11084810, Example 7 in WO2010036630 | US11725004, Example 7 in WO2010036630
Type:
Small organic molecule
Emp. Form.:
C15H23F3N2O5S
Mol. Mass.:
400.414
SMILES:
CC(C)(CO)c1cc(NC(=O)C(C)(C)S(=O)(=O)CCCC(F)(F)F)on1
Structure:
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