Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM295701
Substrate
n/a
Meas. Tech.
In Vitro Assay
EC50
5.40±n/a nM
Citation
 Riether, D; Binder, FP; Doods, H; Mueller, SG; Nicholson, JR; Sauer, A (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles US Patent  US11084810 Publication Date 8/10/2021 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM295701
Synonyms:
Example 30 in WO2010147792 | US10570125, Example 30 | US11084810, Example 30 in WO2010147792 | US11725004, Example 30 in WO2010147792
Type:
Small organic molecule
Emp. Form.:
C17H30N4O3S
Mol. Mass.:
370.51
SMILES:
CN(CC1CCOCC1)C(C)(C)C(=O)Nc1nnc(s1)C(C)(C)CO
Structure:
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