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Target
Hemagglutinin
Ligand
BDBM525153
Substrate
n/a
Meas. Tech.
Cellular Assay-Influenza Virus Replication PR8 and X31 in Calu-3 Human Bronchial Epithelial Cells
EC50
2.28±n/a nM
Citation
 Boudreault, P; Colombo, null; Leduc, R; Marsault, E; Plancq, B; Richter, M Matriptase inhibitors and uses thereof US Patent  US10988505 Publication Date 4/27/2021 
Target
Name:
Hemagglutinin
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
63081.23
Organism:
n/a
Description:
C5MVR7
Residue:
565
Sequence:
MKAILVVLLYTFATANADTLCIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDKHNGKLCKLRGVAPLHLGKCNAGWILGNPECESLSTASSWSYIVETPSSDNGTCYPGDFIDYEELREQLSSVSSFERFEIFPKTSSWPNHDSNKGVTAACPHAGAKSFYKNLIWLVKKGNSYPKLSKSYINDKGKEVLVLWGIHHPSTSADQQSLYQNADAYVFVGSSRYSKKFKPEIAIRPKVRGQEGRMNYYWTLVEPGDKITFEATGNLVVPRYAFAMERNAGSGIIISDTPVHDCNTTCQTPKGAINTSLPFQNIHPITIGKCPKYVKSTKLRLATGLRNIPSIQSRGLFGAIAGFIEGGWTGMVDGWYGYHHQNEQGSGYAADLKSTQNAIDEITNKVNSVIEKMNTQFTAVGKEFNHLEKRIENLNKKVDDGFLDIWTYNAELLVLLENERTLDYHDSNVKNLYEKVRSQLKNNAKEIGNGCFEFYHKCDNTCMESVKNGTYDYPKYSEEAKLNREEIDGVKLESTRIYQILAIYSTVASSLVLVVSLGAISFWMCSNGSLQCRICI
 
Inhibitor
Name:
BDBM525153
Synonyms:
Ac-QFR-kbt | N-0386 | US10988505, Example 3
Type:
Small organic molecule
Emp. Form.:
C29H36N8O5S
Mol. Mass.:
608.712
SMILES:
CC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1 |r|
Structure:
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