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Target
Hemagglutinin
Ligand
BDBM535849
Substrate
n/a
Meas. Tech.
Determination of Antiviral Activity
IC50
9600±n/a nM
Citation
 Salama, ZB Organosilicon carriers for use in treating infections and/or diseases caused by SARS viruses US Patent  US11241393 Publication Date 2/8/2022 
Target
Name:
Hemagglutinin
Synonyms:
HA | HEMA_I68A0 | Hemagglutinin HA1 chain | Hemagglutinin HA2 chain
Type:
PROTEIN
Mol. Mass.:
63416.64
Organism:
Influenza A virus (strain A/Aichi/2/1968 H3N2)
Description:
ChEMBL_795513
Residue:
566
Sequence:
MKTIIALSYIFCLALGQDLPGNDNSTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGIHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEEMGNGCFKIYHKCDNACIESIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI
  
Inhibitor
Name:
BDBM535849
Synonyms:
US11241393, Sil 25
Type:
Small organic molecule
Emp. Form.:
C36H56O4Si
Mol. Mass.:
580.9129
SMILES:
CCCCCCCCCCCC(=O)O[Si](OC(=O)CCCCCCCCCCC)(c1ccccc1)c1ccccc1
Structure:
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