Reaction Details Report a problem with these data
Target
POU domain, class 5, transcription factor 1
Ligand
BDBM50103514
Substrate
n/a
Meas. Tech.
OCT3 inhibitory activity
IC50
67600±n/a nM
Citation
 Yamashita, H; Suzuki, N OCT3 activity inhibitor containing imidazopyridine derivative as active component, and OCT3 detection agent US Patent  US10149840 Publication Date 12/11/2018 
Target
Name:
POU domain, class 5, transcription factor 1
Synonyms:
OCT3 | OCT4 | OTF-3 | OTF3 | Oct-3 | Oct-4 | Octamer-binding protein 3 | Octamer-binding protein 4 | Octamer-binding transcription factor 3 | PO5F1_HUMAN | POU5F1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38567.64
Organism:
Homo sapiens (Human)
Description:
Q01860
Residue:
360
Sequence:
MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
  
Inhibitor
Name:
BDBM50103514
Synonyms:
CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid | Pepcid Ac | Pepcid Rpd
Type:
Small organic molecule
Emp. Form.:
C8H15N7O2S3
Mol. Mass.:
337.445
SMILES:
NC(=N)Nc1nc(CSCCC(=N)NS(N)(=O)=O)cs1
Structure:
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