Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM309331
Substrate
n/a
Meas. Tech.
δ-Opioid Receptor Binding Assay
Ki
23.6±5.56 nM
Citation
 Lockman, J; Tafesse, L Ring-contracted morphinans and the use thereof US Patent  US9656962 Publication Date 5/23/2017 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM309331
Synonyms:
(2R,3aS,4R,9bS)-12-(cyclopropylmethyl)- N-(4-guanidinobutyl)-3a,8-dibydroxy- 1,2,3,3a,4,5-hexahydro-4,9b-(epimino- ethano)cyclopenta[a]naphthalene-2- carboxamide | US9656962, Compound 7
Type:
Small organic molecule
Emp. Form.:
C25H37N5O3
Mol. Mass.:
455.593
SMILES:
NC(=N)NCCCCNC(=O)[C@H]1C[C@@]2(O)[C@H]3Cc4ccc(O)cc4[C@]2(C1)CCN3CC1CC1 |r,TLB:29:28:13:23.17.16|
Structure:
Search PDB for entries with ligand similarity: