Reaction Details Report a problem with these data
Target
Calmodulin-1
Ligand
BDBM588484
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
IC50
1410±n/a nM
Citation
 Bumcrot, DA; Sehgal, A; Hertzog, DL Phenothiazine derivatives and uses thereof US Patent  US11542290 Publication Date 1/3/2023 
Target
Name:
Calmodulin-1
Synonyms:
CALM | CALM1 | CALM1_HUMAN | CALM2 | CAM | CAM1 | CAM2 | CAMB | Calmodulin-2
Type:
Protein
Mol. Mass.:
16813.73
Organism:
Human
Description:
P0DP23
Residue:
149
Sequence:
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
  
Inhibitor
Name:
BDBM588484
Synonyms:
US11542290, Compound MT-002
Type:
Small organic molecule
Emp. Form.:
C21H23F3N2S
Mol. Mass.:
392.481
SMILES:
FC(F)(F)c1ccc2Sc3ccccc3N(CCCN3CCCCC3)c2c1
Structure:
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