Reaction Details Report a problem with these data
Target
Calmodulin-1
Ligand
BDBM588510
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
IC50
4830±n/a nM
Citation
 Bumcrot, DA; Sehgal, A; Hertzog, DL Phenothiazine derivatives and uses thereof US Patent  US11542290 Publication Date 1/3/2023 
Target
Name:
Calmodulin-1
Synonyms:
CALM | CALM1 | CALM1_HUMAN | CALM2 | CAM | CAM1 | CAM2 | CAMB | Calmodulin-2
Type:
Protein
Mol. Mass.:
16813.73
Organism:
Human
Description:
P0DP23
Residue:
149
Sequence:
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
  
Inhibitor
Name:
BDBM588510
Synonyms:
US11542290, Compound MT-028
Type:
Small organic molecule
Emp. Form.:
C25H31F3N4O3S
Mol. Mass.:
524.599
SMILES:
OC[C@@H](O)CNC(=O)CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 |r|
Structure:
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