Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM250244
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay on Mouse TAAR1
Ki
8.20±n/a nM
Citation
 Groebke Zbinden, K; Norcross, R; Pfileger, P Substituted benzamides US Patent  US11697636 Publication Date 7/11/2023 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mus musculus (Mouse)
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM250244
Synonyms:
US11697636, Example 154 | US9452980, 154
Type:
Small organic molecule
Emp. Form.:
C19H20Cl2N2O
Mol. Mass.:
363.281
SMILES:
Clc1ccc(cc1Cl)C(=O)Nc1ccc(CCC2CCCN2)cc1
Structure:
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