Reaction Details Report a problem with these data
Target
Hemagglutinin
Ligand
BDBM611015
Substrate
n/a
Meas. Tech.
Biological Activity
IC50
1.000±n/a nM
Citation
 Jonckers, TH; McGowan, DC; Guilllemont, J; Cooymans, LP; Embrechts, WC; Buyck, CF; Balemans, WM; Raboisson, PJ Heterocyclic indoles for use in influenza virus infection US Patent  US10626108 Publication Date 4/21/2020 
Target
Name:
Hemagglutinin
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
38441.02
Organism:
n/a
Description:
P12590
Residue:
344
Sequence:
MKAKLLVLLCAFTATDADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGNCSIAGWILGNPECESLFSKKSWSYIAETPNSENGTCYPGYFADYEELREQLSSVSSFERFEIFPKESSWPNHTVTKGVTAACSHKGKSSFYRNLLWLTEKNGSYPNLSKSYVNNKEKEVLVLWGVHHPSNIGDQRAIYHTENAYVSVVSSHYNRRFTPEIAKRPKVRGQEGRINYYWTLLEPEDTIIFEANGNLIAPWYAFALSRGFGSGIITSNASMDECDAKCQTPQGAINSSLPFQNVHPVTIGECPKYVRSTKLRMVTGLRNIPSIQSR
 
Inhibitor
Name:
BDBM611015
Synonyms:
US10626108, Compound 13
Type:
Small organic molecule
Emp. Form.:
C24H24F3N7O
Mol. Mass.:
483.4889
SMILES:
Cc1nc(nc(N[C@H]2CCC[C@H](C2)NC(=O)c2cn(C)cn2)c1F)-c1c[nH]c2c(F)cc(F)cc12 |r|
Structure:
Search PDB for entries with ligand similarity: