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Target
Interleukin-17F
Ligand
BDBM617661
Substrate
n/a
Meas. Tech.
AlphaLISA Assay
IC50
63.1±n/a nM
Citation
 MARTIN, BP; WESTERMANN, J; KERN, OT; HOLMES, AJ; MORRISON, A; KICZUN, M; AL MASRI, M; SMITH, A; HUXLEY, A IL-17A MODULATORS US Patent  US20230286943 Publication Date 9/14/2023 
Target
Name:
Interleukin-17F
Synonyms:
Cytokine ML-1 | IL17F | IL17F_HUMAN | il-17f
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18053.35
Organism:
Homo sapiens (Human)
Description:
Q96PD4
Residue:
163
Sequence:
MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
  
Inhibitor
Name:
BDBM617661
Synonyms:
US20230286943, Example 129
Type:
Small organic molecule
Emp. Form.:
C25H32N6O3
Mol. Mass.:
464.56
SMILES:
CCc1nocc1C(=O)N[C@@H](C1CCCCCC1)C(=O)Nc1ccc(nc1)-c1c(C)n[nH]c1C |r|
Structure:
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