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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM314290
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
34.8±n/a nM
Citation
 Torrens-Jover, A; Christmann, U; Diaz-Fernández, J; Almansa-Rosales, C 1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders US Patent  US9611229 Publication Date 4/4/2017 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor, sigma 1 | Oprs1 | SGMR1_MOUSE | Sigma 1-type opioid receptor | Sigma1-receptor | Sigma1R | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25246.51
Organism:
Mus musculus (Mouse)
Description:
O55242
Residue:
223
Sequence:
MPWAAGRRWAWITLILTIIAVLIQAAWLWLGTQNFVFSREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCILHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWKEGTTKSEVFYPGETVVHGPGEATALEWGPNTWMVEYGRGVIPSTLFFALADTFFSTQDYLTLFYTLRAYARGLRLELTTYLFGQDS
  
Inhibitor
Name:
BDBM314290
Synonyms:
1-(3,4- dichlorobenzyl)-N- (3-(piperidin-1- yl)propyl)-1H-1,2,3- triazol-4-amine hydrochloride | US9611229, 10
Type:
Small organic molecule
Emp. Form.:
C17H23Cl2N5
Mol. Mass.:
368.304
SMILES:
Clc1ccc(Cn2cc(NCCCN3CCCCC3)nn2)cc1Cl
Structure:
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