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Target
PPAR delta protein
Ligand
BDBM50192829
Substrate
n/a
Meas. Tech.
Luciferase Assay
EC50
5.06±n/a nM
Citation
 Downes, M; Evans, R; Kluge, A; Lagu, B; Miura, M; Panigrahi, SK; Patane, M; Samajdar, S; Senaiar, R; Takahashi, T PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof US Patent  US10188627 Publication Date 1/29/2019 
Target
Name:
PPAR delta protein
Synonyms:
PPAR delta
Type:
n/a
Mol. Mass.:
49664.60
Organism:
Rattus norvegicus (Rat)
Description:
Q62879
Residue:
440
Sequence:
MEQPQEETPEAREEEKEEVATGDGAPELNGGPEHTLPSSSCTDLSQNSSPSSLLDQLQMGCDGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLKYEKCDRICKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTASEGCQQNPQLADLKAFSKHIYNAYLKNFNMTKKKARSILTGKSSHNAPFIIHDIETLWQAEKGLVWKQLVNGPPPYNEISVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTHEFLRSIRKPFSDIIEPKFEFAVKFNALELVDSDLALFIAAIILCGDRPGLMNVPQVEAIQDTILQALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLKKTESETLLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50192829
Synonyms:
CHEMBL3958704 | US10188627, Compound 8a
Type:
Small organic molecule
Emp. Form.:
C26H27NO5
Mol. Mass.:
433.4963
SMILES:
CN(Cc1ccccc1OC\C=C(/C)CCC(O)=O)C(=O)c1ccc(cc1)-c1ccco1
Structure:
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