Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM191563
Substrate
n/a
Meas. Tech.
β-Lactamase Enzyme Inhibitory Assay
pH
7±n/a
IC50
650±0 nM
Comments
extracted
Citation
 Abe, T; Okue, M; Sakamaki, Y Compounds useful for producing an optically active diazabicyclooctane compound US Patent  US9676777 Publication Date 6/13/2017 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_PSEAE | ampC | beta-Lactamase
Type:
Enzyme
Mol. Mass.:
43406.87
Organism:
Pseudomonas aeruginosa (PAO1)
Description:
P24735
Residue:
397
Sequence:
MRDTRFPCLCGIAASTLLFATTPAIAGEAPADRLKALVDAAVQPVMKANDIPGLAVAISLKGEPHYFSYGLASKEDGRRVTPETLFEIGSVSKTFTATLAGYALTQDKMRLDDRASQHWPALQGSRFDGISLLDLATYTAGGLPLQFPDSVQKDQAQIRDYYRQWQPTYAPGSQRLYSNPSIGLFGYLAARSLGQPFERLMEQQVFPALGLEQTHLDVPEAALAQYAQGYGKDDRPLRVGPGPLDAEGYGVKTSAADLLRFVDANLHPERLDRPWAQALDATHRGYYKVGDMTQGLGWEAYDWPISLKRLQAGNSTPMALQPHRIARLPAPQALEGQRLLNKTGSTNGFGAYVAFVPGRDLGLVILANRNYPNAERVKIAYAILSGLEQQGKVPLKR
  
Inhibitor
Name:
BDBM191563
Synonyms:
US9676777, example 23
Type:
Small organic molecule
Emp. Form.:
C7H11N3O3
Mol. Mass.:
185.1805
SMILES:
NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2O |r|
Structure:
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